Raw Data
The C. elegans 3' UTRome v2 resource for studying mRNA cleavage and polyadenylation, 3'-UTR biology, and miRNA targeting
Hannah S Steber, Christina Gallante, Shannon O'Brien, Po-Lin Chiu and Marco Mangone
Genome Research (2017) 2019 Dec;29(12):2104-2116. doi: 10.1101/gr.254839.119
Alternative polyadenylation directs tissue specific miRNA targeting in Caenorhabditis elegans somatic tissues
Blazie S, Geissel H, Wilky H, Joshi R, Newbern J and Mangone M
Genetics (2017) https://doi.org/10.1534/genetics.116.196774
Comparative RNA-Seq analysis reveals pervasive tissue-specific alternative polyadenylation in Caenorhabditis elegans intestine and muscles
Blazie S, Babb C, Wilky H, Rawls A, Park J and Mangone M
BMC Biology (2015) 13:4 doi:10.1186/s12915-015-0116-6
Recent 3' UTR Papers
Alternative Polyadenylation Directs Tissue Specific miRNA Targeting in Caenorhabditis elegans Somatic Tissues. Genetics 2017 Genetics.116.196774.
Comparative RNA-Seq analysis reveals pervasive tissue-specific alternative polyadenylation in Caenorhabditis elegans intestine and muscles. BMC Biology 2015 Jan 20
Analysis of C. elegans intestinal gene expression and polyadenylation by fluorescence-activated nuclei sorting and 3'-end-seq. Nucleic Acids Res. 2012 Jul 40(13):6304-18
Regulation of mRNA translation and stability by microRNAs Annu Rev Biochem. 2010;79:351-79.
News
- July 26 2019
The new 3'UTRome V2 and the updated MiRanda target prediction have been uploaded in GBrowse
- March 18 2016
The 3'UTRome website has been moved to ASU
Funding
The UTRome Project is currently funded by the National Institute of General Medical Sciences (NIH/NIGMS R01 GM118796)